UAB Digital Repository of Documents 5 records found  Search took 0.02 seconds. 
1.
12 p, 3.9 MB Characterization of Patient-Derived GNAQ Mutated Endothelial Cells from Capillary Malformations / Langbroek, Ginger Beau (University of Amsterdam) ; Stor, Merem L.E. (University of Amsterdam) ; Janssen, Vera (University of Amsterdam) ; de Haan, Annett (University of Amsterdam) ; Horbach, Sophie E.R. (University of Amsterdam) ; Graupera, Mariona (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; van Noesel, Carel J.M. (University of Amsterdam) ; van der Horst, Chantal M.A.M. (University of Amsterdam) ; Wolkerstorfer, Albert (University of Amsterdam) ; Huveneers, Sthephan (University of Amsterdam)
Capillary malformations (CM) (port-wine stains) are congenital skin lesions that are characterized by dilated capillaries and postcapillary venules. CMs are caused by altered functioning of the vascular endothelium. [...]
2023 - 10.1016/j.jid.2023.10.033
The Journal of investigative dermatology, 2023  
2.
10 p, 1.1 MB Identification of Gene Mutations and Fusion Genes in Patients with Sézary Syndrome / Prasad, Aparna (Hospital del Mar (Barcelona, Catalunya)) ; Rabionet, Raquel (Hospital del Mar (Barcelona, Catalunya)) ; Espinet, Blanca (Hospital del Mar (Barcelona, Catalunya)) ; Zapata, Luis (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Puiggros, Anna (Hospital del Mar (Barcelona, Catalunya)) ; Melero, Carme (Hospital del Mar (Barcelona, Catalunya)) ; Puig, Anna (Hospital del Mar (Barcelona, Catalunya)) ; Sarria-Trujillo, Yaris (Hospital del Mar (Barcelona, Catalunya)) ; Ossowski, Stephan (Universitat Pompeu Fabra) ; Garcia Muret, Maria Pilar (Institut d'Investigació Biomèdica Sant Pau) ; Estrach, Teresa (Hospital Clínic i Provincial de Barcelona) ; Servitje, Octavio (Hospital Universitari de Bellvitge) ; Lopez-Lerma, Ingrid (Hospital Universitari Vall d'Hebron) ; Gallardo, Fernando (Hospital del Mar (Barcelona, Catalunya)) ; Pujol Vallverdú, Ramón M (Hospital del Mar (Barcelona, Catalunya)) ; Estivill, Xavier (Hospital del Mar (Barcelona, Catalunya)) ; Universitat Autònoma de Barcelona
Sézary syndrome is a leukemic form of cutaneous T-cell lymphoma with an aggressive clinical course. The genetic etiology of the disease is poorly understood, with chromosomal abnormalities and mutations in some genes being involved in the disease. [...]
2016 - 10.1016/j.jid.2016.03.024
The Journal of investigative dermatology, Vol. 136 Núm. 7 (january 2016) , p. 1490-1499  
3.
21 p, 1.2 MB PAR2 Pepducin-Based Suppression of Inflammation and Itch in Atopic Dermatitis Models / Barr, T.P. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ; Garzia, C. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ; Guha, S. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ; Fletcher, E.K. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ; Nguyen, N. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ; Wieschhaus, A.J. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ; Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Covic, L. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research) ; Kuliopulos, A. (Tufts University School of Medicine. Center of Hemostasis and Thrombosis Research)
PAR2 has been proposed to contribute to lesion formation and intense itch in atopic dermatitis. Here, we tested the ability of a cell-penetrating pepducin, PZ-235, to mitigate the potentially deleterious effects of PAR2 in models of atopic dermatitis. [...]
2019 - 10.1016/j.jid.2018.08.019
The Journal of investigative dermatology, Vol. 139 Núm. 2 (february 2019) , p. 412-421  
4.
8 p, 2.3 MB Paradoxical Benefits of Psychological Stress in Inflammatory Dermatoses Models Are Glucocorticoid Mediated / Lin, Tzu-Kai (College of Medicine, National Cheng Kung University. Institute of Clinical Medicine) ; Man, Mao-Qiang (University of California, San Francisco. Dermatology Service) ; Santiago, Juan-Luis (Hospital General Universitario de Ciudad Real) ; Scharschmidt, Tiffany C. (University of California, San Francisco. Dermatology Service) ; Hupe, Melanie (University of California, San Francisco. Dermatology Service) ; Martin-Ezquerra, Gemma (Institut Hospital del Mar d'Investigacions Mèdiques) ; Youm, Jong-Kyung (University of California, San Francisco. Dermatology Service) ; Zhai, Yongjiao (University of California, San Francisco. Dermatology Service) ; Trullas, Carles (ISDIN) ; Feingold, Kenneth R. (University of California, San Francisco. Dermatology Service) ; Elias, Peter M. (University of California, San Francisco. Dermatology Service) ; Universitat Autònoma de Barcelona
Acute psychological stress (PS) mobilizes metabolic responses that are of immediate benefit to the host, but the current medical paradigm holds that PS exacerbates systemic and cutaneous inflammatory disorders. [...]
2014 - 10.1038/jid.2014.265
The Journal of investigative dermatology, Vol. 134 (08 2014) , p. 2890-2897  
5.
20 p, 1.3 MB Basis for enhanced barrier function of pigmented skin / Man, Mao-Qiang (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Lin, Tzu-Kai (Graduate Institute of Clinical Medicine, National Cheng Kung University Medical College & Department of Dermatology, Tainan, Taiwan) ; Santiago, Juan Luis (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Celli, Anna (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Zhong, Lily (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Huang, Zhi-Ming (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Roelandt, Truus (Department of Dermatology, Universitair Ziekenhuis Brussel, Brussels, Belgium) ; Hupe, Melanie (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Sundberg, John P. (Department of Research and Development, The Jackson Laboratory, Bar Harbor, ME) ; Silva, Kathleen A. (Department of Research and Development, The Jackson Laboratory, Bar Harbor, ME) ; Crumrine, Debra (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Martin-Ezquerra, Gemma (Institut Hospital del Mar d'Investigacions Mèdiques) ; Trullas, Carles (ISDIN, Research & Development, Barcelona, Spain) ; Sun, Richard (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Wakefield, Joan S. (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Wei, Maria L. (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Feingold, Kenneth R. (Medical Service, Department of Veterans Affairs Medical Center, and Department of Metabolism, UCSF, San Francisco, CA) ; Mauro, Theodora M. (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Elias, Peter M. (Dermatology Service, Department of Veterans Affairs Medical Center, and Department of Dermatology, UCSF, San Francisco, CA) ; Universitat Autònoma de Barcelona. Departament de Medicina
Humans with darkly-pigmented skin display superior permeability barrier function in comparison to humans with lightly-pigmented skin. The reduced pH of the stratum corneum (SC) of darkly-pigmented skin could account for enhanced function, because acidifying lightly-pigmented human SC resets barrier function to darkly-pigmented levels. [...]
2014 - 10.1038/jid.2014.187
The Journal of investigative dermatology, Vol. 134 (april 2014) , p. 2399-2407  

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